Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | VDR | P11473 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564919 | 0.84 | MAPT (0.53) | MAPTPOLBL3MBTL1VDRAR | |
| SCHEMBL11935643 | 0.77 | RAD52 (0.34) | MAPTPOLBL3MBTL1VDRAR | |
| SCHEMBL13566039 | 0.76 | BCHE (0.36) | MAPTPOLBL3MBTL1EPHX1GUCY1A1 | |
| SCHEMBL13565217 | 0.75 | HDAC1 (0.35) | MAPTPOLBVDRARGUCY1A1 | |
| SCHEMBL13564774 | 0.75 | MAPT (0.39) | MAPTPOLBL3MBTL1VDRAR | |
| SCHEMBL13565231 | 0.75 | PKM (0.41) | MAPTPOLBL3MBTL1EPHX1LMNA | |
| SCHEMBL13462703 | 0.75 | HCAR3 (0.38) | MAPTEPHX1LMNASMN1; SMN2HTT | |
| SCHEMBL11935350 | 0.75 | BRD4 (0.38) | MAPTALDH1A1GAA | |
| SCHEMBL17090327 | 0.74 | TP53 (0.41) | MAPTPOLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13565878 | 0.74 | HRH3 (0.37) | MAPTSMN1; SMN2HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |