Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10115479 | 0.84 | ALDH1A1 (0.49) | GRIA2GRIA4CTSBCTSS | |
| SCHEMBL13564995 | 0.84 | NPY5R (0.44) | NPY5RGRIA1GRIA2 | |
| SCHEMBL13564802 | 0.83 | GRIA1 (0.54) | NPY5RGRIA1GRIA4 | |
| SCHEMBL13565845 | 0.83 | GRIA1 (0.54) | NPY5RGRIA1GRIA4 | |
| SCHEMBL11935701 | 0.82 | NPY5R (0.46) | NPY5RCA12CA1CA2MMP2 | |
| SCHEMBL13566030 | 0.80 | GRIA1 (0.61) | NPY5RGRIA1GRIA4 | |
| SCHEMBL13564968 | 0.78 | GRIA1 (0.59) | NPY5RGRIA1GRIA2GRIA4CA1 | |
| SCHEMBL11935729 | 0.78 | GRIA1 (0.59) | NPY5RGRIA1GRIA4 | |
| SCHEMBL11935071 | 0.78 | GRIA1 (0.54) | NPY5RGRIA1GRIA2GRIA4 | |
| SCHEMBL13565051 | 0.78 | GRIA1 (0.54) | NPY5RGRIA1GRIA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |