Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935832 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17090053 | 0.83 | ALDH1A1 (0.60) | ALDH1A1USP2TSHRMAPK1RECQL | |
| SCHEMBL10115448 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL11935038 | 0.83 | GRIA1 (0.47) | ALDH1A1GRIA1TSHRMAPK1RECQL | |
| SCHEMBL13564965 | 0.83 | POLB (0.48) | ALDH1A1GRIA1TSHRRECQLPOLB | |
| SCHEMBL17090428 | 0.82 | ALDH1A1 (0.44) | ALDH1A1USP2GRIA1TSHRRECQL | |
| SCHEMBL11935041 | 0.81 | GRIA1 (0.49) | ALDH1A1USP2GRIA1MAPK1RECQL | |
| SCHEMBL11935690 | 0.81 | ALDH1A1 (0.67) | ALDH1A1USP2TSHRMAPK1RECQL | |
| SCHEMBL13565714 | 0.80 | GRIA1 (0.44) | ALDH1A1GRIA1TSHRMAPK1RECQL | |
| SCHEMBL17090440 | 0.79 | GRIA1 (0.51) | ALDH1A1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |