Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 12/20 | 0.37 |
| ▸ | CCR1 | P32246 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565112 | 1.00 | NPY5R (0.37) | NPY5RCCR1CYP3A4CYP2C8SIGMAR1 | |
| SCHEMBL17090205 | 0.91 | NPY5R (0.38) | NPY5RCCR1CYP3A4CYP2C8OPRM1 | |
| SCHEMBL13565097 | 0.87 | OPRM1 (0.39) | NPY5RCCR1CYP3A4CYP2C8SIGMAR1 | |
| SCHEMBL10114806 | 0.85 | ALDH1A1 (0.46) | CCR1OPRM1 | |
| SCHEMBL13439141 | 0.85 | OPRM1 (0.37) | CCR1SIGMAR1OPRM1OPRL1 | |
| SCHEMBL17090383 | 0.84 | NPY5R (0.41) | NPY5RCCR1CYP3A4CYP2C8 | |
| SCHEMBL13565102 | 0.84 | NPY5R (0.41) | NPY5RCCR1CYP3A4CYP2C8 | |
| SCHEMBL13564892 | 0.82 | NPY5R (0.38) | NPY5R | |
| SCHEMBL17090255 | 0.82 | NPY5R (0.38) | NPY5R | |
| SCHEMBL13565342 | 0.80 | CCR1 (0.45) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |