Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565182 | 1.00 | TDP1 (0.44) | TDP1RXFP1LMNAALDH1A1USP2 | |
| SCHEMBL17090428 | 0.88 | ALDH1A1 (0.44) | RXFP1LMNAALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL17090270 | 0.86 | SMN1; SMN2 (0.44) | TDP1RXFP1LMNAALDH1A1USP2 | |
| SCHEMBL13565248 | 0.86 | SMN1; SMN2 (0.44) | TDP1RXFP1LMNAALDH1A1USP2 | |
| SCHEMBL10134141 | 0.86 | ALDH1A1 (0.51) | TDP1RXFP1LMNAALDH1A1USP2 | |
| SCHEMBL10115272 | 0.86 | ALDH1A1 (0.51) | TDP1RXFP1LMNAALDH1A1USP2 | |
| SCHEMBL11935720 | 0.84 | HTR1A (0.51) | NPY5R | |
| SCHEMBL11940090 | 0.84 | HTR1A (0.51) | NPY5R | |
| SCHEMBL11935832 | 0.83 | ALDH1A1 (0.53) | LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL13565220 | 0.80 | HSD17B10 (0.53) | RXFP1LMNAALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |