Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13496725 | 0.91 | HTT (0.46) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL9998464 | 0.91 | HTT (0.46) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL14072750 | 0.90 | MAPT (0.56) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL14945226 | 0.87 | HTT (0.54) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL14072701 | 0.86 | MAPT (0.52) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL14072765 | 0.86 | MAPT (0.52) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL14867811 | 0.86 | HTT (0.49) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL13496729 | 0.85 | MEN1 (0.49) | HTTLMNAMEN1MAPTKMT2A | |
| Iodide SCHEMBL26184954 | 0.85 | MAPT (0.51) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL17790015 | 0.85 | MEN1 (0.43) | HTTLMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | MILLIPORE CORPORATION (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088262-A1 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE | CASP7, MCL1, CARS1 | HTT 994/4885LMNA 1445/4885MEN1 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.