Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12965833 | 0.74 | FABP6 (0.45) | FABP6KDM4EMEN1KMT2AMAPT | |
| SCHEMBL17090693 | 0.71 | BRD4 (0.35) | ALDH1A1PKM | |
| SCHEMBL12965983 | 0.67 | KEAP1 (0.40) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4904552 | 0.63 | KEAP1 (0.44) | FABP6KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5044365 | 0.63 | ALDH1A1 (0.37) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13188450 | 0.63 | FABP6 (0.32) | FABP6KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4419450 | 0.63 | KEAP1 (0.40) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL23159411 | 0.62 | CA1 (0.34) | KDM4ELMNACYP2A6KEAP1 | |
| SCHEMBL5040720 | 0.62 | SMYD3 (0.40) | KDM4EMAPTALDH1A1LMNACYP2A6 | |
| SCHEMBL890167 | 0.62 | NPY5R (0.37) | FABP6KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139569-B2 | Fused tricyclic aryl compounds useful for the treatment of viral diseases | MERCK SHARP & DOHME CORP. (US) | 2015-09-22 | — | — | US | disclosed |