Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6044619 | 0.98 | TSHR (0.61) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL26742630 | 0.93 | TSHR (0.59) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL3553218 | 0.88 | TSHR (0.57) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL23729602 | 0.86 | TSHR (0.77) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL21155013 | 0.85 | TSHR (0.70) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL22418053 | 0.84 | TSHR (0.68) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL16489191 | 0.84 | TSHR (0.73) | TSHRHPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL23478140 | 0.83 | TSHR (0.65) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL3149173 | 0.83 | TSHR (0.53) | TSHRCNR1HPGDSMN1; SMN2HTT | |
| SCHEMBL24164565 | 0.83 | TSHR (0.67) | TSHRCNR1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| EP-2481427-A1 | Folate-Tubulysin conjugates | Endocyte, Inc. (US) | 2012-08-01 | — | — | EP | disclosed |