Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699754 | 0.86 | KDM4E (0.59) | NCEH1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL10385035 | 0.82 | LMNA (0.72) | KDM4EGAALMNAL3MBTL1BCHE | |
| Hydrochloric Acid SCHEMBL29611600 | 0.81 | LMNA (0.71) | KDM4EGAALMNAL3MBTL1BCHE | |
| SCHEMBL1709101 | 0.80 | KDM4E (0.53) | NCEH1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL19182434 | 0.72 | KDM4E (0.64) | NCEH1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL11372888 | 0.70 | KDM4E (0.54) | NCEH1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL9101160 | 0.69 | LMNA (0.66) | KDM4EGAALMNAL3MBTL1BCHE | |
| SCHEMBL1709100 | 0.69 | NCEH1 (0.54) | NCEH1LMNABCHEACHE | |
| SCHEMBL23698707 | 0.69 | KDM4E (0.65) | NCEH1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL13021655 | 0.68 | KDM4E (0.55) | NCEH1KDM4ELMNAL3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691992-B2 | Octahydro biquinoline compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-04-08 | — | — | US | disclosed |
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | CYP2S1, HCRTR2, CYP2B6 | NCEH1 73/4885KDM4E 681/4885GAA 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.