Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385035 | 0.85 | LMNA (0.72) | LMNAL3MBTL1BCHEMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL29611600 | 0.84 | LMNA (0.71) | LMNAL3MBTL1BCHEMETAP2METAP1 | |
| SCHEMBL10750474 | 0.80 | LMNA (0.63) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL17266841 | 0.80 | BCHE (0.53) | LMNAL3MBTL1BCHE | |
| SCHEMBL10751843 | 0.79 | HSP90AA1 (0.63) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL10424862 | 0.78 | L3MBTL1 (0.63) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL7364217 | 0.78 | L3MBTL1 (0.62) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL250301 | 0.77 | LMNA (0.65) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL10751742 | 0.77 | LMNA (0.60) | LMNAL3MBTL1METAP2METAP1HDAC6 | |
| SCHEMBL28459061 | 0.77 | LMNA (0.69) | LMNAL3MBTL1METAP2METAP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245505-B2 | TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER | ASAHI CHEMICAL IND (JP) | 1996-08-14 | — | — | EP | claimed |