Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 13/20 | 0.74 |
| ▸ | LGALS1 | P09382 | 8/20 | 0.74 |
| ▸ | LGALS9 | O00182 | 6/20 | 0.74 |
| ▸ | LGALS7; LGALS7B | P47929 | 5/20 | 0.74 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.64 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | HK2 | P52789 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434972 | 1.00 | LGALS3 (0.74) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2434970 | 1.00 | LGALS3 (0.74) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2430098 | 0.88 | LGALS3 (0.77) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2430103 | 0.88 | LGALS3 (0.77) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL5450852 | 0.88 | LGALS3 (0.77) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2432200 | 0.86 | LGALS3 (0.74) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2432203 | 0.86 | LGALS3 (0.74) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2430865 | 0.85 | LGALS3 (0.77) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL2430861 | 0.85 | LGALS3 (0.77) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 | |
| SCHEMBL22790271 | 0.85 | LGALS3 (1.00) | LGALS3LGALS1LGALS9LGALS7; LGALS7BLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2919802-A1 | METHODS, COMPOSITIONS AND KITS FOR TREATING, MODULATING, OR PREVENTING OCULAR ANGIOGENESIS OR FIBROSIS IN A SUBJECT USING A GALECTIN PROTEIN INHIBITOR | Tufts University (US) | 2015-09-23 | — | — | EP | disclosed |