Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.64 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17091631 | 1.00 | GPR119 (0.64) | GPR119ROCK1 | |
| SCHEMBL288283 | 1.00 | GPR119 (0.64) | GPR119ROCK1 | |
| SCHEMBL3233374 | 0.90 | GPR119 (0.66) | GPR119 | |
| SCHEMBL3241662 | 0.90 | GPR119 (0.78) | GPR119 | |
| SCHEMBL3233358 | 0.90 | GPR119 (0.66) | GPR119 | |
| SCHEMBL3241658 | 0.90 | GPR119 (0.78) | GPR119 | |
| SCHEMBL3233365 | 0.90 | GPR119 (0.66) | GPR119 | |
| SCHEMBL3241667 | 0.90 | GPR119 (0.78) | GPR119 | |
| SCHEMBL299959 | 0.86 | GPR119 (0.80) | GPR119 | |
| SCHEMBL2717368 | 0.85 | GPR119 (0.72) | GPR119ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210886-B1 | PYRIMIDYL INDOLINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-09-23 | — | — | EP | claimed |