Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | CTSG | P08311 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481207 | 0.84 | TSHR (0.57) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL1709296 | 0.83 | CYP1A2 (0.46) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL1705697 | 0.81 | TSHR (0.50) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL1703204 | 0.81 | TSHR (0.50) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9160111 | 0.81 | TSHR (0.50) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL8903502 | 0.77 | TSHR (0.49) | TSHRPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9613415 | 0.77 | CNR2 (0.49) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL1709304 | 0.76 | CA1 (0.46) | TSHRKMT2AALDH1A1 | |
| SCHEMBL1709334 | 0.76 | TSHR (0.47) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL1709301 | 0.76 | TSHR (0.47) | TSHRSMN1; SMN2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | TSHR 3526/4885PRSS1 3517/4885CTSG 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.