Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172659 | 0.84 | TAAR1 (0.45) | TAAR1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL23269924 | 0.84 | ALDH1A1 (0.42) | ACHETAAR1ALDH1A1HPGDALOX15 | |
| SCHEMBL22520955 | 0.81 | TAAR1 (0.59) | ACHETAAR1PKMSMN1; SMN2 | |
| SCHEMBL170728 | 0.81 | ACHE (0.46) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL29257739 | 0.79 | ACHE (0.44) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL9046621 | 0.78 | ACHE (0.43) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL21612989 | 0.76 | ACHE (0.41) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL22763796 | 0.76 | ACHE (0.50) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL170719 | 0.76 | ACHE (0.50) | ACHETAAR1PKMEEDALDH1A1 | |
| SCHEMBL20843260 | 0.75 | CD44 (0.46) | ACHETAAR1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |