⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709289 | 1.00 | — | — | |
| SCHEMBL268198 | 1.00 | — | — | |
| Acetic Acid SCHEMBL28852386 | 0.92 | TDP1 (0.38) | — | |
| Ethyl Acetate SCHEMBL28852383 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL15992208 | 0.81 | MMP1 (0.41) | — | |
| SCHEMBL11128512 | 0.81 | TDP1 (0.37) | — | |
| SCHEMBL2528138 | 0.79 | — | — | |
| SCHEMBL11466259 | 0.79 | — | — | |
| SCHEMBL637645 | 0.79 | — | — | |
| SCHEMBL2153461 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222902-A1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2018-08-09 | — | — | US | disclosed |
| US-9796710-B2 | Dihydropyrrolopyridine inhibitors of ROR-gamma | VITAE PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170173168-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170081327-A1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2017-03-23 | — | — | US | disclosed |
| US-9481674-B1 | Dihydropyrrolopyridine inhibitors of ROR-gamma | VITAE PHARMACEUTICALS, INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160002286-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY | 2016-01-07 | — | — | US | disclosed |
| US-9051310-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20140309225-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
| US-4628120-A | REARRANGEMENTS USING ORGANOALUMINUM COMPOUNDS | TOYO STAUFFER CHEMICAL CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
| US-4604486-A | PINACOL-TYPE REARRANGEMENT OF SOLFONYLOXY ALCOHOLS IN PRESENCE FO ORGANOALUMINUM COMPOUNDS | TOYO STAUFFER CHEMICAL CO., LTD. (JP) | 1986-08-05 | — | — | US | disclosed |