Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709475 | 0.90 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 | |
| SCHEMBL13836640 | 0.83 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 | |
| SCHEMBL1709511 | 0.80 | MAOA (0.38) | SLC6A2SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL2316984 | 0.79 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 | |
| SCHEMBL1709365 | 0.78 | MAOA (0.36) | SLC6A2SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL2317133 | 0.76 | PSEN1 (0.42) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 | |
| SCHEMBL2318915 | 0.76 | PSEN1 (0.47) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 | |
| SCHEMBL1709455 | 0.76 | MAOA (0.35) | SLC6A2SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL6918642 | 0.76 | MAOA (0.39) | SLC6A2SLC6A4PSEN1PSEN2APH1B | |
| SCHEMBL6917403 | 0.75 | PSEN1 (0.46) | SLC6A2SLC6A4SLC6A3PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |