Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709511 | 0.95 | MAOA (0.38) | MAOAKDM1AMAOBHTR2CMTOR | |
| SCHEMBL1709455 | 0.89 | MAOA (0.35) | MAOAKDM1AMAOBHTR2CMTOR | |
| SCHEMBL1709475 | 0.88 | SLC6A2 (0.45) | MAOAKDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL1709370 | 0.88 | GPBAR1 (0.37) | MAOAKDM1AMAOBMTORSLC6A2 | |
| SCHEMBL1709494 | 0.87 | HTR2C (0.35) | MAOAKDM1AMAOBHTR2CSLC6A4 | |
| SCHEMBL6918642 | 0.87 | MAOA (0.39) | MAOAKDM1AMAOBLTA4HHTR2C | |
| SCHEMBL1709404 | 0.86 | HTR2C (0.34) | MAOAKDM1AMAOBHTR2CSLC6A4 | |
| SCHEMBL1709443 | 0.86 | HTR2C (0.34) | MAOAKDM1AMAOBHTR2CSLC6A4 | |
| SCHEMBL1709403 | 0.86 | HTR2C (0.34) | MAOAKDM1AMAOBHTR2CSLC6A4 | |
| SCHEMBL10032823 | 0.83 | HTR2C (0.34) | MAOAKDM1AMAOBHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |