Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032981 | 0.89 | GPBAR1 (0.40) | GPBAR1TSHRSLC18A2MAOAKDM1A | |
| SCHEMBL1709365 | 0.88 | MAOA (0.36) | MAOAKDM1AMAOBMTORSLC6A2 | |
| SCHEMBL10032983 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL1709440 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL1709511 | 0.83 | MAOA (0.38) | MAOAKDM1AMAOBMTORNPSR1 | |
| SCHEMBL6918642 | 0.81 | MAOA (0.39) | MAOAKDM1AMAOBMTORSLC6A2 | |
| SCHEMBL10033181 | 0.81 | KDM4E (0.33) | SLC18A2SLC6A4 | |
| SCHEMBL1709436 | 0.81 | KDM4E (0.33) | SLC18A2SLC6A4 | |
| SCHEMBL1709475 | 0.79 | SLC6A2 (0.45) | MAOALMNAKDM1AMAOBGPR88 | |
| SCHEMBL1709455 | 0.78 | MAOA (0.35) | MAOALMNAKDM1AMAOBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |