Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726094 | 0.88 | GPR6 (0.35) | GPR6BRD4POLBMAPK14 | |
| SCHEMBL9997403 | 0.88 | AR (0.37) | GPR6BRD4SLC22A12GPR119AR | |
| SCHEMBL168453 | 0.88 | POLB (0.33) | POLB | |
| SCHEMBL171000 | 0.82 | AR (0.45) | GPR6SLC22A12GPR119ARMAPK14 | |
| SCHEMBL173682 | 0.81 | POLB (0.40) | GPR6SLC22A12GPR119ARSCN9A | |
| SCHEMBL1726006 | 0.80 | AR (0.46) | GPR6SLC22A12GPR119ARICMT | |
| SCHEMBL1726550 | 0.76 | AR (0.38) | SLC22A12ARPOLB | |
| SCHEMBL173769 | 0.75 | HSD11B1 (0.36) | ARPOLB | |
| SCHEMBL169379 | 0.72 | AR (0.47) | SLC22A12GPR119ARICMTPOLB | |
| SCHEMBL30415275 | 0.69 | MAPT (0.46) | POLBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | claimed |
| EP-2403834-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-12-02 | — | — | EP | claimed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | claimed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | claimed |
| US-10448639-B2 | Fungicidal pyrazoles | FMC CORPORATION (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9655361-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-23 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| EP-2403834-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-12-02 | — | — | EP | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| US-9062005-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | disclosed |
| WO-2010101973-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | GPR6 1425/4885BRD4 1287/4885SLC22A12 3193/4885 |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | GPR6 4206/4885BRD4 3659/4885SLC22A12 4500/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | GPR6 4206/4885BRD4 3659/4885SLC22A12 4500/4885 |
| US-10448639-B2 | Fungicidal pyrazoles | CBR3, CBR1, CYP2S1 | GPR6 1425/4885BRD4 1287/4885SLC22A12 3193/4885 |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | GPR6 1425/4885BRD4 1287/4885SLC22A12 3193/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | GPR6 4206/4885BRD4 3659/4885SLC22A12 4500/4885 |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | GPR6 1425/4885BRD4 1287/4885SLC22A12 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.