SCHEMBL1709618

SCHEMBL1709618

CCN(CC)CCCS(=O)(=O)N[C@H](CCc1ccccc1)c1nc(C2COc3ccccc3O2)n[nH]1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 2/20 0.58
LTA4H P09960 6/20 0.37
RAB9A P51151 1/20 0.37
KLF5 Q13887 1/20 0.37
CYSLTR2 Q9NS75 9/20 0.32
CYSLTR1 Q9Y271 9/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709681 0.89 GHSR (0.56) GHSRCYSLTR2CYSLTR1
SCHEMBL1709676 0.88 GHSR (0.56) GHSR
SCHEMBL1709598 0.86 GHSR (0.58) GHSRSMN1; SMN2
SCHEMBL1989435 0.84 GHSR (0.62) GHSR
SCHEMBL1709668 0.84 GHSR (0.54) GHSR
SCHEMBL1709621 0.81 GHSR (0.56) GHSR
SCHEMBL1991846 0.78 GHSR (0.71) GHSRRAB9ASMN1; SMN2
SCHEMBL1995494 0.78 GHSR (0.57) GHSRRAB9ASMN1; SMN2
SCHEMBL10121926 0.77 GHSR (0.67) GHSR
SCHEMBL1709708 0.77 GHSR (0.67) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120088747-A1 SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF ELIXIR PHARMACEUTICALS, INC. 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088747-A1 SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF GHSR, GHRHR, STS GHSR 1/4885LTA4H 1780/4885RAB9A 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.