Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 3/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709579 | 0.99 | GHSR (0.46) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709670 | 0.98 | GHSR (0.45) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709694 | 0.87 | GHSR (0.48) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709692 | 0.87 | GHSR (0.48) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709666 | 0.86 | GHSR (0.43) | GHSRGAAF2CCR5 | |
| SCHEMBL1709735 | 0.86 | GHSR (0.47) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709729 | 0.86 | GHSR (0.48) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709691 | 0.85 | GHSR (0.44) | GHSRTSHRRAB9ACCR5 | |
| SCHEMBL1709734 | 0.85 | GHSR (0.49) | GHSRGAASCN1ASCN2ASCN3A | |
| SCHEMBL1709679 | 0.85 | GHSR (0.47) | GHSRGAASCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | ELIXIR PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | GHSR, GHRHR, STS | GHSR 1/4885GAA 55/4885SCN1A 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.