Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHAT | P28329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17092828 | 1.00 | TRPA1 (0.41) | TRPA1EGFRTYRTDP1TP53 | |
| SCHEMBL27742021 | 0.83 | TRPA1 (0.51) | TRPA1EGFRMAPTKDM4ECHAT | |
| SCHEMBL23856117 | 0.79 | TRPA1 (0.40) | TRPA1EGFRTDP1TP53MAPT | |
| SCHEMBL23856118 | 0.79 | TRPA1 (0.40) | TRPA1EGFRTDP1TP53MAPT | |
| SCHEMBL919137 | 0.79 | AHR (0.49) | EGFRTTRALOX5PTGS1PTGS2 | |
| SCHEMBL919139 | 0.79 | AHR (0.49) | EGFRTTRALOX5PTGS1PTGS2 | |
| SCHEMBL6470750 | 0.79 | AHR (0.49) | EGFRTTRALOX5PTGS1PTGS2 | |
| SCHEMBL8105367 | 0.78 | TYR (0.42) | TRPA1EGFRTYRTDP1TP53 | |
| SCHEMBL8770707 | 0.78 | TYR (0.48) | EGFRTYRTDP1TP53MAPT | |
| SCHEMBL2356473 | 0.75 | BID (0.54) | MAPTKDM4EALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119839-B1 | TRI-SUBSTITUTED AROMATIC-CONTAINING ADDITIVES AND SURFACTANTS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2019-08-14 | — | — | EP | disclosed |
| US-9650323-B2 | Tri-substituted aromatic-containing additives and surfactants and methods for use | RHODIA OPERATIONS (FR) | 2017-05-16 | — | — | US | disclosed |
| EP-3119839-A1 | TRI-SUBSTITUTED AROMATIC-CONTAINING ADDITIVES AND SURFACTANTS AND METHODS FOR USE | Rhodia Operations (FR) | 2017-01-25 | — | — | EP | disclosed |
| US-20150267035-A1 | TRI-SUBSTITUTED AROMATIC-CONTAINING ADDITIVES AND SURFACTANTS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2015-09-24 | — | — | US | disclosed |
| WO-2015143050-A1 | TRI-SUBSTITUTED AROMATIC-CONTAINING ADDITIVES AND SURFACTANTS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150267035-A1 | TRI-SUBSTITUTED AROMATIC-CONTAINING ADDITIVES AND SURFACTANTS AND METHODS FOR USE | TYR, TLR3, TPST2 | TRPA1 36/4885EGFR 2554/4885TYR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.