Sugi Predict

Sugi Predict / Compounds / SCHEMBL17097374

SCHEMBL17097374

SCHEMBL17097374

Brc1ccc(-c2ccccc2)c([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.40
▸ MAPK1 P28482 3/20 0.40
▸ PTPRC P08575 1/20 0.40
▸ NPC1 O15118 4/20 0.38
▸ RAB9A P51151 4/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ PRKD3 O94806 2/20 0.38
▸ MAP4K4 O95819 2/20 0.38
▸ FER P16591 2/20 0.38
▸ CDK2 P24941 2/20 0.38
▸ MARK3 P27448 2/20 0.38
▸ FLT4 P35916 2/20 0.38
▸ FLT3 P36888 2/20 0.38
▸ CLK2 P49760 2/20 0.38
▸ CSNK2A1 P68400 2/20 0.38
▸ MAP4K2 Q12851 2/20 0.38
▸ STK3 Q13188 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16115917 0.81 NPC1 (0.41) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL17097377 0.79 ALDH1A1 (0.41) ALDH1A1MAPK1PTPRCNPC1RAB9A
SCHEMBL28528140 0.79 ALDH1A1 (0.46) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL16115423 0.76 ALDH1A1 (0.41) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL30332661 0.76 ALDH1A1 (0.41) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL30006434 0.73 MAPK1 (0.52) ALDH1A1MAPK1PTPRCNPC1RAB9A
SCHEMBL19190198 0.73 PTPRC (0.56) ALDH1A1MAPK1PTPRCNPC1RAB9A
SCHEMBL364027 0.73 MAPK1 (0.52) ALDH1A1MAPK1PTPRCNPC1RAB9A
SCHEMBL538592 0.72 ALDH1A1 (0.46) ALDH1A1MAPK1PTPRCNPC1RAB9A
SCHEMBL16115916 0.72 ALDH1A1 (0.39) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10629830-B2 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-21 — — US disclosed
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-01-18 — — US disclosed
US-9780317-B2 Amine derivative, organic luminescent material and organic electroluminescent device using the amine derivative or the organic luminescent material SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-03 — — US disclosed
US-20150270502-A1 AMINE DERIVATIVE, ORGANIC LUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE AMINE DERIVATIVE OR THE ORGANIC LUMINESCENT MATERIAL SAMSUNG DISPLAY CO., LTD. (KP) 2015-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE ARL1, RIF1, LARS1 ALDH1A1 531/4885MAPK1 861/4885PTPRC 4844/4885
US-10629830-B2 Organic electroluminescent device ARL1, RIF1, LARS1 ALDH1A1 531/4885MAPK1 861/4885PTPRC 4844/4885
US-20150270502-A1 AMINE DERIVATIVE, ORGANIC LUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE AMINE DERIVATIVE OR THE ORGANIC LUMINESCENT MATERIAL ARL1, RIF1, LARS1 ALDH1A1 591/4885MAPK1 854/4885PTPRC 4871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.