SCHEMBL364027

SCHEMBL364027

Brc1ccc(-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.52
ALDH1A1 P00352 3/20 0.52
PTPRC P08575 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.49
ALOX5 P09917 1/20 0.48
S100A4 P26447 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
BACE1 P56817 1/20 0.44
ESR2 Q92731 1/20 0.43
CYP19A1 P11511 1/20 0.42
CYP2A6 P11509 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
DCLK1 O15075 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30006434 1.00 MAPK1 (0.52) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL2200354 0.95 MAPK1 (0.61) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL2171715 0.95 MAPK1 (0.61) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL19190198 0.95 PTPRC (0.56) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL2200357 0.91 NPC1 (0.47) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL28399888 0.89 ALDH1A1 (0.48) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL28866753 0.89 ALDH1A1 (0.48) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL30523586 0.88 CYP1A2 (0.52) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL30223283 0.88 CYP1A2 (0.52) MAPK1ALDH1A1PTPRCPTGDR2ALOX5
SCHEMBL28459829 0.86 HSD17B10 (0.56) MAPK1ALDH1A1PTPRCPTGDR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824474-A The preparation method of one kind 3,5- diphenyl bromobenzene 辽宁博美医药科技有限公司 2019-05-31 CN claimed
CN-119684308-A Compound for organic luminescent material and application thereof 西安瑞联新材料股份有限公司 2025-03-25 CN disclosed
CN-114685411-B Organic compound, application thereof and organic electroluminescent device 北京鼎材科技有限公司 2025-03-21 CN disclosed
CN-113511978-B Compound, application thereof and organic electroluminescent device using same 北京鼎材科技有限公司 2024-10-15 CN disclosed
CN-113045481-B Compound and application thereof, and organic electroluminescent device comprising compound 合肥鼎材科技有限公司 2024-10-01 CN disclosed
CN-114437006-B Organic compound and application thereof 北京鼎材科技有限公司 2024-09-27 CN disclosed
CN-118620152-A Polyarylimidazole polymers, preparation and hydrogen ion selective membranes 山西大学 2024-09-10 CN disclosed
CN-113620817-B Compound and application thereof 北京鼎材科技有限公司 2024-08-13 CN disclosed
CN-114773273-B Organic blue light small molecule based on phenanthroimidazole and application thereof in preparation of undoped organic electroluminescent device 吉林大学 2024-08-06 CN disclosed
CN-113861041-B Compound and application thereof 北京鼎材科技有限公司 2024-07-09 CN disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
CN-1332944-C Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate SHANGHAI INST ORGANIC CHEM (CN) 2007-08-22 CN disclosed
CN-1934909-A Material for organic electroluminescent element and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2007-03-21 CN disclosed
CN-1651408-A Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate SHANGHAI INST ORGANIC CHEM (CN) 2005-08-10 CN disclosed
EP-0905172-A1 POLYSILANES AND POSITIVE HOLE TRANSPORTING MATERIALS OSAKA GAS CO., LTD. (JP) 1999-03-31 EP disclosed
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP disclosed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US disclosed
EP-0396943-A2 Optical storage medium and storage process NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-11-14 EP disclosed
US-4143077-A BROMINATING, THEN IODINATING M-TERPHENYL, ETHERIFYING WITH AN ALKALI METAL PHENOLATE INSTITUT FRANCAIS DU PETROLE (FR) 1979-03-06 US disclosed
US-3957666-A HYDRAULIC FLUIDS, HEAT TRANSFER FLUIDS MONSANTO COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DDC, TYR, EML4 MAPK1 2533/4885ALDH1A1 546/4885PTPRC 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.