Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27396622 | 0.90 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPK1SYKAKT1 | |
| SCHEMBL29077734 | 0.90 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPK1SYKAKT1 | |
| SCHEMBL13150768 | 0.85 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPK1SYKAKT1 | |
| SCHEMBL28131444 | 0.81 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPK1SYKAKT1 | |
| SCHEMBL7703626 | 0.80 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MAPK1SYKSMN1; SMN2 | |
| SCHEMBL418232 | 0.80 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1MAPK1SYKAKT1 | |
| SCHEMBL1626511 | 0.79 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPK1SYKSMN1; SMN2 | |
| SCHEMBL27003934 | 0.78 | HDAC3 (0.45) | L3MBTL1ALDH1A1MAPK1SYKSMN1; SMN2 | |
| SCHEMBL31170532 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1MAPK1SYKSMN1; SMN2 | |
| SCHEMBL24208084 | 0.77 | BACE1 (0.42) | L3MBTL1ALDH1A1MAPK1SYKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047617-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2012-04-12 | — | — | WO | disclosed |