Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100605 | 1.00 | KMT2A (0.54) | KMT2AMEN1GBA1L3MBTL1GAA | |
| SCHEMBL17100829 | 0.91 | ALDH1A1 (0.54) | KMT2AGBA1LMNAPOLBPKM | |
| SCHEMBL17100881 | 0.91 | ALDH1A1 (0.54) | KMT2AGBA1LMNAPOLBPKM | |
| SCHEMBL17100726 | 0.91 | ALDH1A1 (0.54) | KMT2AGBA1LMNAPOLBPKM | |
| SCHEMBL17100644 | 0.89 | KDM2B (0.42) | KMT2AMEN1GBA1L3MBTL1NPSR1 | |
| SCHEMBL17100932 | 0.81 | L3MBTL1 (0.58) | KMT2AMEN1GBA1L3MBTL1GAA | |
| SCHEMBL17100701 | 0.79 | KMT2A (0.53) | KMT2AMEN1GBA1L3MBTL1GAA | |
| SCHEMBL17100911 | 0.77 | SMN1; SMN2 (0.56) | KMT2AMEN1GBA1L3MBTL1GAA | |
| SCHEMBL17100840 | 0.76 | KMT2A (0.52) | KMT2AMEN1GBA1L3MBTL1GAA | |
| SCHEMBL17100931 | 0.76 | KMT2A (0.52) | KMT2AMEN1GBA1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |