Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CLPP | Q16740 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100853 | 1.00 | NPSR1 (0.52) | NPSR1LMNAKDM4EMAPTTP53 | |
| SCHEMBL17100858 | 0.87 | LMNA (0.57) | NPSR1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL17100661 | 0.86 | LMNA (0.55) | NPSR1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL17100723 | 0.86 | ALDH1A1 (0.51) | NPSR1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL17100651 | 0.83 | SMN1; SMN2 (0.46) | LMNAMAPTKMT2AMEN1RAB9A | |
| SCHEMBL17100623 | 0.81 | KMT2A (0.57) | NPSR1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL17100600 | 0.77 | NPSR1 (0.45) | NPSR1LMNAKDM4EMAPTTP53 | |
| SCHEMBL17100613 | 0.77 | ABCC1 (0.42) | RAB9ASMN1; SMN2 | |
| SCHEMBL17100743 | 0.77 | ALDH1A1 (0.56) | LMNAKDM4EMAPTKMT2ARAB9A | |
| SCHEMBL17115076 | 0.76 | SOS1 (0.44) | CLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119774-A1 | OXADIAZOLE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140130-A1 | OXADIAZOLE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |