Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101484 | 0.86 | ADRB2 (0.51) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL1827610 | 0.84 | ADRB2 (0.66) | ADRB2ADRB1DRD2ADRA1DABCB11 | |
| SCHEMBL27810572 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1DRD2ADRA1DABCB11 | |
| SCHEMBL1827166 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1DRD2ADRA1DABCB11 | |
| Bromide SCHEMBL1825951 | 0.81 | ADRB2 (0.62) | ADRB2ADRB1DRD2ADRA1DABCB11 | |
| SCHEMBL2214870 | 0.79 | ADRB2 (0.53) | ADRB2 | |
| SCHEMBL524144 | 0.79 | ADRB2 (0.59) | ADRB2 | |
| SCHEMBL2209783 | 0.79 | ADRB2 (0.59) | ADRB2 | |
| Bromide SCHEMBL1682997 | 0.78 | ADRB2 (0.59) | ADRB2 | |
| SCHEMBL435245 | 0.78 | ADRB2 (0.56) | ADRB2ADRB1DRD2ADRA1DABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119752-A1 | CHEMICAL COMPOUNDS | Astrazeneca AB (SE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140527-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2015-09-24 | — | — | WO | disclosed |