Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827166 | 0.98 | ADRB2 (0.63) | ADRB2ABCB11ADRB1DRD2ADRA1D | |
| Bromide SCHEMBL1825951 | 0.97 | ADRB2 (0.62) | ADRB2ABCB11ADRB1DRD2ADRA1D | |
| SCHEMBL4443114 | 0.91 | ADRB2 (0.68) | ADRB2ABCB11 | |
| SCHEMBL2211009 | 0.89 | ADRB2 (0.67) | ADRB2ABCB11ADRB1DRD2 | |
| SCHEMBL2211014 | 0.87 | ADRB2 (0.65) | ADRB2ABCB11ADRB1DRD2 | |
| SCHEMBL27810572 | 0.87 | ADRB2 (0.56) | ADRB2ABCB11ADRB1DRD2ADRA1D | |
| SCHEMBL435245 | 0.84 | ADRB2 (0.56) | ADRB2ABCB11ADRB1DRD2ADRA1D | |
| SCHEMBL17101482 | 0.84 | ADRB2 (0.51) | ADRB2ABCB11ADRB1DRD2ADRA1D | |
| Trifluoroacetic Acid SCHEMBL2208487 | 0.84 | ADRB2 (0.49) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL4434958 | 0.83 | ADRB2 (0.67) | ADRB2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341966-A1 | INHALER WITH AUDIBLE INDICATOR MEANS | AstraZeneca AB (SE) | 2011-07-13 | — | — | EP | claimed |
| US-20110253138-A1 | INHALER WITH AUDIBLE INDICATOR MEANS | ASTRAZENECA AB (SE) | 2011-10-20 | — | — | US | disclosed |
| EP-2121642-B1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2011-07-27 | — | — | EP | disclosed |
| EP-2315589-A1 | PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST | AstraZeneca AB (SE) | 2011-05-04 | — | — | EP | disclosed |