Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940233 | 0.85 | BDKRB2 (0.59) | BDKRB2CYP3A4 | |
| SCHEMBL1710166 | 0.80 | BDKRB2 (0.59) | BDKRB2CYP3A4 | |
| SCHEMBL1710190 | 0.77 | BDKRB2 (0.55) | BDKRB2CYP3A4 | |
| SCHEMBL1564611 | 0.72 | BDKRB2 (0.59) | BDKRB2CYP3A4 | |
| SCHEMBL13146259 | 0.72 | BDKRB2 (0.58) | BDKRB2CYP3A4 | |
| SCHEMBL2939769 | 0.70 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL2939461 | 0.70 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL13145116 | 0.69 | BDKRB2 (1.00) | BDKRB2 | |
| SCHEMBL13180133 | 0.68 | BDKRB2 (0.69) | BDKRB2CYP3A4 | |
| SCHEMBL2944592 | 0.68 | BDKRB2 (0.53) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344477-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010031589-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-03-25 | — | — | WO | claimed |
| EP-2344477-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010031589-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-03-25 | — | — | WO | disclosed |