Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220769 | 1.00 | MAOB (0.38) | MAOBMAOAHSD11B1SLC6A3SLC22A2 | |
| SCHEMBL28842496 | 0.81 | SLC22A2 (0.36) | SLC22A2SLC22A1SLC22A3SIGMAR1OPRM1 | |
| SCHEMBL17115021 | 0.81 | HSD11B1 (0.45) | MAOBMAOAHSD11B1SLC6A3SLC22A2 | |
| SCHEMBL28842444 | 0.81 | SLC22A2 (0.36) | SLC22A2SLC22A1SLC22A3PLAUNOS1 | |
| SCHEMBL28842621 | 0.80 | MAOA (0.43) | MAOBMAOASLC6A3PLAUAPP | |
| SCHEMBL876037 | 0.80 | AKR1C1 (0.44) | MAOBMAOAHSD11B1SLC22A2SLC22A1 | |
| SCHEMBL838361 | 0.80 | AKR1C1 (0.44) | MAOBMAOAHSD11B1SLC22A2SLC22A1 | |
| SCHEMBL31459729 | 0.79 | KDM1A (0.45) | HSD11B1SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL21824468 | 0.77 | CA1 (0.42) | CYP2C19 | |
| SCHEMBL21824467 | 0.77 | CA1 (0.42) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096653-A1 | COMPOSITIONS AND INHIBITORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-115066418-A | Carboxy derivatives with anti-inflammatory properties | 西特瑞治疗有限公司 | 2022-09-16 | — | — | CN | disclosed |
| EP-3119782-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | reMynd NV (BE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140132-A1 | 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS | REMYND NV (BE) | 2015-09-24 | — | — | WO | disclosed |