Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL17102688 | 0.90 | HDAC8 (0.41) | HTTHDAC8NPSR1APOBEC3AAPOBEC3G | |
| Sulfuric Acid SCHEMBL17102586 | 0.87 | HDAC8 (0.38) | HTTHDAC8APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL1534053 | 0.78 | HDAC8 (0.39) | HTTHDAC8NPSR1LMNAAPOBEC3A | |
| SCHEMBL28722829 | 0.74 | APOBEC3A (0.42) | HTTHDAC8NPSR1LMNAAPOBEC3A | |
| SCHEMBL11272078 | 0.73 | HDAC8 (0.35) | HTTHDAC8NPSR1LMNAAPOBEC3A | |
| SCHEMBL15559765 | 0.68 | HTT (0.42) | HTTHDAC8NPSR1LMNAAPOBEC3A | |
| SCHEMBL19548308 | 0.68 | HTT (0.42) | HTTHDAC8NPSR1LMNAAPOBEC3A | |
| SCHEMBL31460613 | 0.66 | HDAC8 (0.45) | HTTHDAC8NPSR1APOBEC3AAPOBEC3G | |
| Sulfuric Acid SCHEMBL2866328 | 0.66 | HDAC8 (0.45) | HTTHDAC8NPSR1APOBEC3AAPOBEC3G | |
| SCHEMBL4024967 | 0.65 | MAPT (0.47) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9147919-B2 | Methods of producing sulfate salts of cations from heteroatomic compounds and dialkyl sulfates and uses thereof | FLUIDIC, INC. (US) | 2015-09-29 | — | — | US | disclosed |