Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11305412 | 0.81 | HDAC8 (0.46) | HDAC8NPSR1KDM4EAPOBEC3ASMN1; SMN2 | |
| SCHEMBL1534053 | 0.77 | HDAC8 (0.39) | HDAC8NPSR1HTTLMNAKDM4E | |
| SCHEMBL28722829 | 0.73 | APOBEC3A (0.42) | HDAC8NPSR1HTTLMNAKDM4E | |
| SCHEMBL17102702 | 0.73 | HTT (0.37) | HDAC8NPSR1HTTLMNAKDM4E | |
| SCHEMBL538961 | 0.72 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL6738038 | 0.72 | PSMD14 (0.32) | — | |
| 2-Pyrrolidone SCHEMBL421593 | 0.70 | OR51E2 (0.33) | — | |
| Sulfuric Acid SCHEMBL11316454 | 0.70 | CA1 (0.35) | — | |
| SCHEMBL4453948 | 0.70 | — | — | |
| SCHEMBL28599017 | 0.69 | LMNA (0.32) | NPSR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042938-A1 | Homopolymers and copolymers of 1,3-dialkyl-2-alkenylimidazolium salts | AMERICAN CYANAMID COMPANY (US) | 1982-01-06 | — | — | EP | claimed |
| US-4299939-A | USED IN WATER TREATMENT OF PARTICULATE SUSPENSIONS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | claimed |
| EP-0042938-A1 | Homopolymers and copolymers of 1,3-dialkyl-2-alkenylimidazolium salts | AMERICAN CYANAMID COMPANY (US) | 1982-01-06 | — | — | EP | disclosed |
| US-4299939-A | USED IN WATER TREATMENT OF PARTICULATE SUSPENSIONS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |