Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17104298 | 1.00 | LMNA (0.42) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17104334 | 1.00 | LMNA (0.42) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17104299 | 1.00 | LMNA (0.42) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17104329 | 1.00 | LMNA (0.42) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL17104304 | 1.00 | LMNA (0.42) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL24464886 | 0.97 | LMNA (0.43) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL12652354 | 0.92 | LMNA (0.43) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL15534730 | 0.85 | ADH1B (0.54) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL10066725 | 0.85 | ADH1B (0.54) | LMNAADH1BADH1CADH1AADH4 | |
| SCHEMBL2360620 | 0.85 | ADH1B (0.54) | LMNAADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421874-B1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2015-09-30 | — | — | EP | claimed |