SCHEMBL17109014

SCHEMBL17109014

c1ccc(-n2c3ccccc3c3c4oc5c(ccc6c5c5ccccc5n6-c5cccc(-c6cccc7c6sc6ccccc67)c5)c4ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 8/20 0.39
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
BRCA1 P38398 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16483865 0.98 ALOX5 (0.44) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16171137 0.92 ALOX5 (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16484383 0.92 ALOX5 (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18505634 0.90 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15137638 0.90 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL18620334 0.90 PRKDC (0.37) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16283023 0.90 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16483879 0.89 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16482243 0.89 PRKDC (0.38) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL16171138 0.88 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 ALOX5 1455/4885PRKDC 4771/4885PIK3CD 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.