Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775826 | 0.88 | PDE5A (0.53) | MEN1KMT2AAURKATP53MAPT | |
| SCHEMBL15635777 | 0.85 | LMNA (0.58) | MEN1KMT2AAURKAALDH1A1HTT | |
| SCHEMBL15636037 | 0.84 | DHODH (0.58) | MEN1KMT2AAURKAMAPTALDH1A1 | |
| SCHEMBL869587 | 0.82 | DHODH (0.46) | MEN1KMT2AAURKAMAPTALDH1A1 | |
| SCHEMBL870223 | 0.82 | DHODH (0.53) | MEN1KMT2AAURKAALDH1A1CYP1A2 | |
| SCHEMBL4874399 | 0.81 | MEN1 (0.49) | MEN1KMT2ATP53MAPTALDH1A1 | |
| SCHEMBL17110898 | 0.81 | MEN1 (0.68) | AKR1C3AKR1C2MEN1KMT2AAURKA | |
| SCHEMBL3455093 | 0.81 | MEN1 (0.67) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL4767292 | 0.81 | PDE4B (0.44) | MEN1KMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL17110964 | 0.81 | ANO1 (0.47) | AKR1C3AKR1C2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144977-A1 | TRPA1 MODULATORS | ORIEN CORPORATION (FI) | 2015-10-01 | — | — | WO | disclosed |