Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.56 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.56 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083914 | 0.91 | ALDH1A1 (0.75) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL21844925 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL19569940 | 0.87 | ALDH1A1 (0.75) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL2956853 | 0.87 | — | — | |
| SCHEMBL19288507 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL14301397 | 0.82 | HPGD (0.68) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL24746586 | 0.81 | HTT (0.62) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL24003551 | 0.79 | CHRNB2 (0.48) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL20083911 | 0.79 | HTT (0.46) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL26162910 | 0.78 | HTT (0.46) | ALDH1A1HPGDTSHRCHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125925-A1 | COMPOSITIONS FOR TREATING DRY AGE-RELATED MACULAR DEGENERATION (AMD) | COGNITION THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-3210609-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2017-08-30 | — | — | EP | disclosed |
| WO-2015140133-A1 | PIPERIDINE-DIONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015142903-A2 | METHOD OF CONTROLLING LACTATE PRODUCTION WITH PIPERDINE-DIONE DERIVATIVES | GENENTECH, INC. (US) | 2015-09-24 | — | — | WO | disclosed |