Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 10/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426012 | 0.77 | NPC1 (0.46) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL3331863 | 0.77 | NPC1 (0.47) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL10272992 | 0.77 | FAAH (0.50) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL6920576 | 0.75 | NPC1 (0.44) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL18901151 | 0.74 | NPC1 (0.63) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL24921043 | 0.73 | FAAH (0.43) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL11646668 | 0.73 | SMN1; SMN2 (0.53) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL1272691 | 0.71 | FAAH (0.45) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL6048162 | 0.71 | FAAH (0.47) | NPC1RAB9AKDM4EFAAHDAGLA | |
| SCHEMBL1272689 | 0.71 | FAAH (0.42) | NPC1RAB9AKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435019-B1 | DODECA-2E,4E-DIENE AMIDES AND THEIR USE AS MEDICAMENTS AND COSMETICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2015-09-23 | — | — | EP | disclosed |