Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051920 | 0.88 | SETD7 (0.41) | SETD7ACHEMAPK1BCHE | |
| SCHEMBL19051924 | 0.88 | SETD7 (0.41) | SETD7ACHEMAPK1BCHE | |
| SCHEMBL19051918 | 0.88 | SETD7 (0.41) | SETD7ACHEMAPK1BCHE | |
| SCHEMBL19024329 | 0.76 | MAOA (0.36) | HRH4MAOBMAOASETD7MAPK1 | |
| SCHEMBL19051925 | 0.76 | MAOA (0.36) | HRH4MAOBMAOASETD7MAPK1 | |
| SCHEMBL19051932 | 0.72 | HTT (0.48) | LMNAACHEMAPK1TP53MAPT | |
| SCHEMBL19051949 | 0.72 | HTT (0.48) | LMNAACHEMAPK1TP53MAPT | |
| SCHEMBL19591718 | 0.70 | MAPK1 (0.52) | LMNAHRH4MAOBMAOAELANE | |
| SCHEMBL9475303 | 0.70 | ELANE (0.62) | LMNAHRH4MAOBMAOAELANE | |
| SCHEMBL19885345 | 0.69 | ELANE (0.50) | LMNAHRH4MAOBMAOASETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143349-A1 | NEW IMAGING AGENTS AND METHODS OF IDENTIFYING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-09-24 | — | — | WO | disclosed |