Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024329 | 1.00 | MAOA (0.36) | MAOAMAOBSTK17BCYP1A2CYP2D6 | |
| SCHEMBL19051918 | 0.87 | SETD7 (0.41) | CYP1A2CYP2D6SETD7MAPK1 | |
| SCHEMBL19051924 | 0.87 | SETD7 (0.41) | CYP1A2CYP2D6SETD7MAPK1 | |
| SCHEMBL19051920 | 0.87 | SETD7 (0.41) | CYP1A2CYP2D6SETD7MAPK1 | |
| SCHEMBL17115226 | 0.83 | CYP1A2 (0.44) | MAOAMAOBSTK17BCYP1A2CYP2D6 | |
| SCHEMBL19051933 | 0.83 | CYP1A2 (0.44) | MAOAMAOBSTK17BCYP1A2CYP2D6 | |
| SCHEMBL17115222 | 0.83 | CYP1A2 (0.44) | MAOAMAOBSTK17BCYP1A2CYP2D6 | |
| SCHEMBL19051943 | 0.78 | HTT (0.44) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL17115236 | 0.76 | LMNA (0.40) | MAOAMAOBSETD7MAPK1HRH4 | |
| SCHEMBL19051932 | 0.71 | HTT (0.48) | CYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | THR TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | THR TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | DDX3X, DDX21, DAXX | MAOA 1520/4885MAOB 1522/4885STK17B 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.