SCHEMBL17117450

SCHEMBL17117450

c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)Sc1cc(-n3c4ccccc4c4ccccc43)ccc1N2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ NOX1 Q9Y5S8 11/20 0.44
▸ GAA P10253 6/20 0.42
▸ MAPT P10636 6/20 0.42
▸ SNCA P37840 6/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ KMT2A Q03164 4/20 0.42
▸ TDP1 Q9NUW8 3/20 0.42
▸ BCHE P06276 2/20 0.42
▸ ACHE P22303 2/20 0.42
▸ ALOX15 P16050 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ MAOA P21397 1/20 0.42
▸ CNR1 P21554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265920 0.95 NOX1 (0.52) L3MBTL1KDM4EATMNOX1GAA
SCHEMBL30361008 0.95 NOX1 (0.52) L3MBTL1KDM4EATMNOX1GAA
SCHEMBL2389888 0.82 KDM4E (0.52) L3MBTL1KDM4EATMBCHEACHE
SCHEMBL22907727 0.82 NOX1 (0.38) L3MBTL1KDM4EATMNOX1GAA
SCHEMBL22907754 0.80 MAPT (0.43) L3MBTL1KDM4ENOX1GAAMAPT
SCHEMBL22907755 0.77 SNCA (0.37) L3MBTL1NOX1GAAMAPTSNCA
SCHEMBL17265886 0.77 KDM4E (0.46) L3MBTL1KDM4EATMMAPTCYP1A2
SCHEMBL30361009 0.77 KDM4E (0.46) L3MBTL1KDM4EATMMAPTCYP1A2
SCHEMBL17109674 0.75 NOX1 (0.47) L3MBTL1KDM4EATMNOX1MAPT
SCHEMBL17265888 0.75 KDM4E (0.44) L3MBTL1KDM4EATMGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9590190-B2 Terminally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2017-03-07 — — US disclosed
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same OCIAD1, OCIAD2, OGFOD1 L3MBTL1 1887/4885KDM4E 3472/4885ATM 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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