Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13507759 | 0.83 | KDM4E (0.43) | KDM4EATML3MBTL1 | |
| SCHEMBL29949424 | 0.83 | L3MBTL1 (0.47) | KDM4EATML3MBTL1ALDH1A1HDAC4 | |
| SCHEMBL17117450 | 0.82 | L3MBTL1 (0.46) | KDM4EATML3MBTL1GPR3CYP1A2 | |
| SCHEMBL17109674 | 0.81 | NOX1 (0.47) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL23954411 | 0.81 | KDM4E (0.44) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL12259331 | 0.81 | KDM4E (0.41) | KDM4EATML3MBTL1EDNRBEDNRA | |
| SCHEMBL12259323 | 0.81 | NOX1 (0.48) | KDM4EATML3MBTL1GPR3 | |
| SCHEMBL28514016 | 0.80 | ATM (0.47) | KDM4EATML3MBTL1ALDH1A1HDAC4 | |
| SCHEMBL29949396 | 0.80 | ATM (0.47) | KDM4EATML3MBTL1ALDH1A1HDAC4 | |
| SCHEMBL24643816 | 0.79 | KDM4E (0.42) | KDM4EATML3MBTL1PTPN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| WO-2014167286-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2014-10-16 | — | — | WO | disclosed |
| US-8012606-B2 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8012606-B2 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8012606-B2 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | KDM4E 4166/4885ATM 4288/4885L3MBTL1 899/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | KDM4E 4166/4885ATM 4288/4885L3MBTL1 899/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | KDM4E 4166/4885ATM 4288/4885L3MBTL1 899/4885 |
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | ORC3, NAP1L4, NR4A2 | KDM4E 1619/4885ATM 3596/4885L3MBTL1 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.