Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111072 | 0.94 | NR1H4 (0.49) | NR1H4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17118234 | 0.91 | KMT2A (0.60) | NPC1RAB9AKMT2AMEN1CA12 | |
| SCHEMBL11590256 | 0.80 | NPC1 (0.66) | NR1H4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10001968 | 0.79 | TDP1 (0.61) | NR1H4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12200275 | 0.77 | RAB9A (0.85) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL25800418 | 0.76 | RAB9A (0.63) | NPC1RAB9AKMT2AMEN1CA12 | |
| SCHEMBL13258146 | 0.76 | KMT2A (0.57) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL17213006 | 0.76 | MEN1 (0.49) | NPC1RAB9AKMT2AMEN1CA12 | |
| SCHEMBL4621112 | 0.75 | CSNK2A1 (0.65) | KMT2AMEN1CA12CA7CA1 | |
| SCHEMBL15293401 | 0.75 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170057870-A1 | CONCRETE FORMULATION AND METHODS OF MAKING | LIGHT POLYMERS HOLDING (KY) | 2017-03-02 | — | — | US | disclosed |
| US-20150266999-A1 | INSOLUBILIZATION OF WATER-SOLUBLE POLYARAMIDE BY CROSS-LINKING WITH POLYFUNCTIONAL AZIRIDINE | LIGHT POLYMERS HOLDING (KY) | 2015-09-24 | — | — | US | disclosed |