Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680548 | 1.00 | FNTA (0.49) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL13078444 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL20698854 | 0.82 | SLC6A4 (0.44) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL7674020 | 0.81 | SLC6A4 (0.59) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL11947490 | 0.81 | SLC6A4 (0.59) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL19123555 | 0.80 | SLC6A4 (0.50) | FNTAFNTBPGGT1BSLC6A4SLC6A2 | |
| SCHEMBL12204727 | 0.79 | ALOX5 (0.41) | SLC6A4SLC6A2SLC6A3CYP2D6ALDH1A1 | |
| SCHEMBL7896140 | 0.76 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3ALDH1A1OPRM1 | |
| SCHEMBL19145747 | 0.76 | ACHE (0.54) | SLC6A4SLC6A2SLC6A3CYP2D6OPRM1 | |
| SCHEMBL11585932 | 0.75 | ACHE (0.69) | SLC6A4SLC6A2SLC6A3CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048134-B1 | MEPTAZINOL BILIGAND DERIVATIVES AND/OR THEIR SALTS, PREPARATION METHOD AND USES THEREOF | UNIV FUDAN (CN) | 2015-09-23 | — | — | EP | disclosed |