Sugi Predict

Sugi Predict / Compounds / SCHEMBL17119893

SCHEMBL17119893

SCHEMBL17119893

Cc1ccc2c(=S)n(C(C)C)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.39
▸ HTR2A P28223 3/20 0.37
▸ HTR2C P28335 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ LMNA P02545 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ CYP2A6 P11509 4/20 0.35
▸ RXFP1 Q9HBX9 2/20 0.35
▸ CA12 O43570 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ NR1I2 O75469 1/20 0.32
▸ EGFR P00533 1/20 0.32
▸ ADRA2A P08913 1/20 0.32
▸ ADORA3 P0DMS8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391523 0.79 MEN1 (0.43) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL22796675 0.77 HTR2A (0.46) CYP1A2HTR2AHTR2CKDM4EALDH1A1
SCHEMBL17121354 0.77 CYP1A2 (0.42) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL24157358 0.75 CYP1A2 (0.41) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL24225329 0.75 KDM4E (0.43) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL599047 0.74 HTR2A (0.53) CYP1A2HTR2AHTR2CMAPTCYP2A6
SCHEMBL26873254 0.72 CYP1A2 (0.39) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL27111367 0.72 MAPT (0.65) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL18418915 0.72 CYP1A2 (0.39) CYP1A2HTR2AHTR2CKDM4ELMNA
SCHEMBL13087059 0.72 CYP1A2 (0.39) CYP1A2KDM4ELMNAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240070422-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-02-29 — — US disclosed
US-11532380-B2 Methods for using nucleic acids to store, retrieve and access information comprising a text, image, video or audio format PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-12-20 — — US disclosed
US-20210241059-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2021-08-05 — — US disclosed
US-11077195-B2 IL-2 conjugates and methods of use thereof Synthorx, Inc. (US) 2021-08-03 — — US disclosed
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS THE SCRIPPS RESEARCH INSTITUTE 2020-12-17 — — US disclosed
US-20200330601-A1 IL-2 Conjugates and Methods of Use Thereof Synthorx, Inc. (US) 2020-10-22 — — US disclosed
US-20200272872-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2020-08-27 — — US disclosed
US-10460220-B2 Methods of storing information using nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-10-29 — — US disclosed
US-20190258909-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-08-22 — — US disclosed
US-10289801-B2 Methods for retrievable information storage using nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-05-14 — — US disclosed
US-20190121936-A1 Methods for Retrievable Information Storage Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2019-04-25 — — US disclosed
US-9996778-B2 Methods of storing information using nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-06-12 — — US disclosed
US-9996778-B2 Methods of storing information using nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-06-12 — — US disclosed
US-20170337324-A1 Methods for Retrievable Information Storage Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2017-11-23 — — US disclosed
US-20170337324-A1 Methods for Retrievable Information Storage Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2017-11-23 — — US disclosed
US-20160358055-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2016-12-08 — — US disclosed
US-9384320-B2 Methods of storing information using nucleic acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-07-05 — — US disclosed
US-20150269313-A1 Methods of Storing Information Using Nucleic Acids PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077195-B2 IL-2 conjugates and methods of use thereof IL2, IL2RA, IL15 CYP1A2 220/4885HTR2A 1281/4885HTR2C 1307/4885
US-20200330601-A1 IL-2 Conjugates and Methods of Use Thereof IL2, IL2RA, IL15 CYP1A2 220/4885HTR2A 1281/4885HTR2C 1307/4885
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS RNGTT, MAX, POLRMT CYP1A2 4841/4885HTR2A 4232/4885HTR2C 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.