SCHEMBL1712062

SCHEMBL1712062

Fc1ccnc(OCc2cc[c]cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 8/20 0.41
MAPK14 Q16539 1/20 0.36
FFAR1 O14842 2/20 0.34
FFAR4 Q5NUL3 2/20 0.34
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ELOVL1 Q9BW60 1/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
CYP1A2 P05177 1/20 0.32
GABRA5 P31644 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711722 0.80 CYP11B1 (0.39) GRM5NPC1ALDH1A1CYP2D6CYP2C19
SCHEMBL1711886 0.80 NPC1 (0.40) GRM5NPC1ALDH1A1CYP2D6CYP2C19
SCHEMBL510247 0.80 MAOB (0.45) GRM5RAB9A
SCHEMBL16093376 0.78 GPR84 (0.40) GRM5MAPK14FFAR1FFAR4ELOVL1
SCHEMBL510603 0.76 MAOA (0.48) GRM5NPC1ALDH1A1MEN1RAB9A
SCHEMBL1712285 0.75 CXCR2 (0.47) GRM5ELOVL1GABRA5
SCHEMBL16093390 0.74 GRM5 (0.38) GRM5MAPK14FFAR1FFAR4ALDH1A1
SCHEMBL1712287 0.74 NPC1 (0.54) GRM5MAPK14NPC1ALDH1A1CYP2D6
SCHEMBL7081299 0.72 KDM4E (0.36) NPC1ALDH1A1CYP2D6CYP2C19MEN1
SCHEMBL509341 0.72 MGMT (0.36) GRM5FFAR1FFAR4ALDH1A1ELOVL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed