SCHEMBL17122004

SCHEMBL17122004

N=CC(=O)OC1C=CCC2C(=O)OC(=O)C12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.33
HK1 P19367 1/20 0.33
HKDC1 Q2TB90 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6215321 0.81 NSD2 (0.48) NSD2HK1HKDC1
SCHEMBL6705482 0.76 KDM4E (0.31) NSD2HK1HKDC1
SCHEMBL10593202 0.72
SCHEMBL17195889 0.69 NSD2 (0.46) NSD2HK1HKDC1
SCHEMBL1071613 0.69 KDM4E (0.33)
SCHEMBL10592596 0.69 KDM4E (0.33)
SCHEMBL6703741 0.67 PPARG (0.31)
SCHEMBL10593375 0.66
SCHEMBL1739727 0.65 KMT2A (0.41)
SCHEMBL1473414 0.65 KMT2A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2924053-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID COMPOUND OR SALT THEREOF Glytech, Inc. (JP) 2015-09-30 EP disclosed