SCHEMBL17124103

SCHEMBL17124103

c1ccc(-n2c3ccc(-c4ccc(-c5ccc6ccc7cccnc7c6n5)cc4)cc3c3cccnc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP2C19 P33261 1/20 0.40
FEN1 P39748 1/20 0.36
PDE4A P27815 6/20 0.36
PDE4B Q07343 5/20 0.36
PDE4C Q08493 5/20 0.36
PDE4D Q08499 5/20 0.36
TOP1 P11387 3/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MMP2 P08253 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
MMP9 P14780 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17124105 1.00 TSHR (0.40) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124057 0.96 TSHR (0.42) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124095 0.94 TSHR (0.39) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17522019 0.92 TSHR (0.38) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124094 0.92 TSHR (0.39) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124051 0.90 TSHR (0.40) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124059 0.90 TSHR (0.40) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL21911925 0.90 ALDH1A1 (0.36) TSHRALDH1A1CYP2C19FEN1PDE4A
SCHEMBL17124104 0.88 LMNA (0.34) TSHRALDH1A1CYP2C19TOP1KDM4E
SCHEMBL17124062 0.88 LMNA (0.34) TSHRALDH1A1CYP2C19TOP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2927978-B1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO LTD (KR) 2020-03-18 EP disclosed
US-10290814-B2 Organic light-emitting diode LG DISPLAY CO., LTD. (KR) 2019-05-14 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed