Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191565 | 0.89 | HRH1 (0.51) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| SCHEMBL29572974 | 0.84 | CYP1A2 (0.69) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| SCHEMBL1760766 | 0.84 | CYP1A2 (0.69) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| SCHEMBL27451530 | 0.82 | L3MBTL1 (0.59) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10981614 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL21752109 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| Bromide SCHEMBL7912525 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| Bromide SCHEMBL6565773 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| SCHEMBL230753 | 0.81 | HRH1 (0.73) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 | |
| SCHEMBL29485678 | 0.81 | HRH1 (0.73) | CYP1A2CYP2D6HRH1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | US | disclosed |
| CN-1960976-A | 4-carbox pyrazole derivates useful as anti-viral agents | SMITHKLINE BEECHAM CORP (US) | 2007-05-09 | — | — | CN | disclosed |
| EP-1730116-A1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092863-A1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| CN-1219780-C | Heterocyclic compounds binding chemotactic factor receptor | ANORMED INC (CA) | 2005-09-21 | — | — | CN | disclosed |
| CN-1351601-A | Heterocyclic compounds binding chemotactic factor receptor | ANORMED INC (CA) | 2002-05-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167507-A1 | 4-Carbox pyrazole derivatives useful as anti-viral agents | HAVCR2, RPL35, ZC3HAV1L | CYP1A2 332/4885CYP2D6 294/4885HRH1 537/4885 |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | CYP1A2 2061/4885CYP2D6 3619/4885HRH1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.