Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 2/20 | 0.70 |
| ▸ | NT5E | P21589 | 7/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | ALB | P02768 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GLI1 | P08151 | 1/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | DPP4 | P27487 | 1/20 | 0.67 |
| ▸ | RORC | P51449 | 1/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.67 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.67 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.67 |
| ▸ | CETP | P11597 | 1/20 | 0.65 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.65 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344383 | 0.93 | PRKCG (0.80) | PRKCGNT5EPTPN1ALBUSP2 | |
| SCHEMBL3787219 | 0.93 | PRKCG (0.80) | PRKCGNT5EPTPN1ALBUSP2 | |
| SCHEMBL3776971 | 0.93 | PRKCG (0.80) | PRKCGNT5EPTPN1ALBUSP2 | |
| SCHEMBL15713556 | 0.93 | PRKCG (0.80) | PRKCGNT5EPTPN1ALBUSP2 | |
| SCHEMBL17124514 | 0.93 | GPBAR1 (0.67) | PRKCGNT5EGPBAR1 | |
| SCHEMBL12330536 | 0.92 | PRKCG (0.68) | PRKCGNT5EPTPN1ALBUSP2 | |
| SCHEMBL15713557 | 0.92 | NT5E (0.70) | PRKCGNT5EUSP2LMNAHIF1A | |
| SCHEMBL3786305 | 0.92 | NT5E (0.70) | PRKCGNT5EUSP2LMNAHIF1A | |
| SCHEMBL3790380 | 0.92 | NT5E (0.70) | PRKCGNT5EUSP2LMNAHIF1A | |
| SCHEMBL16349462 | 0.92 | PRKCG (0.67) | PRKCGNT5EPTPN1ALBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096446-A1 | Extended Triterpene Derivatives | MYREXIS, INC. (US) | 2017-04-06 | — | — | US | disclosed |
| US-20150272922-A1 | Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof | BIONICHE ANIMAL HEALTH USA, INC. | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096446-A1 | Extended Triterpene Derivatives | BET1, PGGT1B, TMPO | PRKCG 1026/4885NT5E 811/4885PTPN1 4535/4885 |
| US-20150272922-A1 | Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof | NR3C1, NR5A1, NR3C2 | PRKCG 1007/4885NT5E 3317/4885PTPN1 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.